Tiffany Scharschmidt, MD

Principal Investigator, Assistant Professor
Department of Dermatology
tiffany.scharschmidt@ucsf.edu
Publications: 

Skin Commensal Antigens: Taking the Road Less Traveled.

Trends in immunology

Dhariwala MO, Scharschmidt TC

Successful treatment of mucous membrane pemphigoid with bortezomib.

JAAD case reports

Saeed L, Schmidt TH, Gensler LS, Gross AJ, Fox LP, Scharschmidt TC, Gaensler K, Naik H, Rosenblum MA, Shinkai K

Skin Dysbiosis Goes "Off-Leish".

Cell host & microbe

Scharschmidt TC

A vitamin to D-crease sunburn.

Science translational medicine

Scharschmidt TC

Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.

Cell

Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, Cotsarelis G, Abbas AK, Rosenblum MD

Measuring inflammation in IBD with an OSM-ostat.

Science translational medicine

Scharschmidt TC

Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.

Cell host & microbe

Scharschmidt TC, Vasquez KS, Pauli ML, Leitner EG, Chu K, Truong HA, Lowe MM, Sanchez Rodriguez R, Ali N, Laszik ZG, Sonnenburg JL, Millar SE, Rosenblum MD

When TLRs fail, IgG has your back.

Science translational medicine

Scharschmidt TC

Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing.

Journal of immunology (Baltimore, Md. : 1950)

Nosbaum A, Prevel N, Truong HA, Mehta P, Ettinger M, Scharschmidt TC, Ali NH, Pauli ML, Abbas AK, Rosenblum MD

A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes.

Immunity

Scharschmidt TC, Vasquez KS, Truong HA, Gearty SV, Pauli ML, Nosbaum A, Gratz IK, Otto M, Moon JJ, Liese J, Abbas AK, Fischbach MA, Rosenblum MD

Paradoxical benefits of psychological stress in inflammatory dermatoses models are glucocorticoid mediated.

The Journal of investigative dermatology

Lin TK, Man MQ, Santiago JL, Scharschmidt TC, Hupe M, Martin-Ezquerra G, Youm JK, Zhai Y, Trullas C, Feingold KR, Elias PM

What Lives On Our Skin: Ecology, Genomics and Therapeutic Opportunities Of the Skin Microbiome.

Drug discovery today. Disease mechanisms

Scharschmidt TC, Fischbach MA

Immune reconstitution reactions in human immunodeficiency virus-negative patients: report of a case and review of the literature.

JAMA dermatology

Scharschmidt TC, Amerson EH, Rosenberg OS, Jacobs RA, McCalmont TH, Shinkai K

Neurogenic rosacea: a distinct clinical subtype requiring a modified approach to treatment.

Archives of dermatology

Scharschmidt TC, Yost JM, Truong SV, Steinhoff M, Wang KC, Berger TG

Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis.

The Journal of investigative dermatology

Gunathilake R, Schmuth M, Scharschmidt TC, Gruber R, Grabher D, Leslie KS, Maurer TA, Mauro TM, Elias PM

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.

The Journal of allergy and clinical immunology

Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM

Matriptase-deficient mice exhibit ichthyotic skin with a selective shift in skin microbiota.

The Journal of investigative dermatology

Scharschmidt TC, List K, Grice EA, Szabo R

Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.

The Journal of investigative dermatology

Hatano Y, Man MQ, Uchida Y, Crumrine D, Scharschmidt TC, Kim EG, Mauro TM, Feingold KR, Elias PM, Holleran WM

Modeling atopic dermatitis with increasingly complex mouse models.

The Journal of investigative dermatology

Scharschmidt TC, Segre JA

Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.

The Journal of biological chemistry

List K, Currie B, Scharschmidt TC, Szabo R, Shireman J, Molinolo A, Cravatt BF, Segre J, Bugge TH

Estrogen receptor beta-selective transcriptional activity and recruitment of coregulators by phytoestrogens.

The Journal of biological chemistry

An J, Tzagarakis-Foster C, Scharschmidt TC, Lomri N, Leitman DC